Posted by: miriamjang | March 24, 2008

Air Pollution and Arterial Damage

Just a note to have your Autistic individual avoid areas with air pollution. Try not to exercise or walk in heavy traffic times and roads.Don’t forget that gasoline fumes also increase the cadmium level in the blood and tissues, adding to the toxic load:

News article from 2002 remains relevant, many newer cites are linked herein:

Pollution strangles blood supply, causes changes to the body
http://news.bbc.co.uk/1/hi/health/1866673.stm

– – Free online, the peer-reviewed article that prompted the news item:

Inhalation of fine particulate air pollution and ozone causes acute arterial vasoconstriction in healthy adults.

Brook RD, Brook JR, Urch B, Vincent R, Rajagopalan S, Silverman F.
University of Michigan, Ann Arbor, USA.
Circulation. 2002 Apr 2;105(13):1534-6.
http://circ.ahajournals.org/cgi/content/full/105/13/1534

BACKGROUND: Fine particulate air pollution and ozone are associated with increased cardiovascular events. To help explain the mechanism behind these observations, we investigated the effect of air pollution exposure on vascular function.
METHODS AND RESULTS: Twenty-five healthy adults underwent a randomized, double-blind, crossover study comparing the vascular response to the 2-hour inhalation of approximately 150 microg/m(3) of concentrated ambient fine particles (CAP) plus ozone (120 ppb) versus the response to the inhalation of filtered air. High-resolution vascular ultrasonography was used to measure alterations in brachial artery diameter, endothelial-dependent flow-mediated dilatation (FMD) and endothelial-independent nitroglycerin-mediated dilatation (NMD). Exposure to CAP plus ozone caused a significant brachial artery vasoconstriction compared with filtered air inhalation (-0.09+/-0.15 mm versus +0.01+/-0.18 mm, P=0.03). There were no significant differences in FMD (+0.29+/-4.11% versus -0.03+/-6.63%, P=0.88), NMD (+3.87+/-5.43% versus +3.46+/-7.92%, P=0.83), or blood pressure responses between exposures.
CONCLUSIONS: Short-term inhalation of fine particulate air pollution and ozone at concentrations that occur in the urban environment causes acute conduit artery vasoconstriction.
PMID: 11927516

This is a medical disclaimer: Please remember that this not meant as medical advice but as a desire to share information. Please always implement treatments under medical supervision. We are cannot be held liable for any of this information.

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