Posted by: miriamjang | January 30, 2008

Autism and Decreased Bone Density

Hi Everyone,

This is a very important new study: that there is decreased bone density in boys on the casein free diet used in the treatment of Autism. Please note that the effects can be mitigated by the use of Vit D and calcium×48156/

Abstract:  Bone development, casein-free diet use, supplements, and medications were assessed for 75 boys with autism or autism spectrum disorder, ages 4–8 years. Second metacarpal bone cortical thickness (BCT), measured on hand-wrist radiographs, and % deviations in BCT from reference medians were derived. BCT increased with age, but % deviations evidenced a progressive fall-off (= .02): +3.1 ± 4.7%, −6.5 ± 4.0%, −16.6 ± 3.4%, −19.4 ± 3.7%, −24.1 ± 4.4%, at ages 4–8, respectively, adjusting for height. The 12% of the boys on casein-free diets had an overall % deviation of −18.9 ± 3.7%, nearly twice that of boys on minimally restricted or unrestricted diets (−10.5 ± 1.3%, < .04), although even for boys on minimally restricted or unrestricted diets the % deviation was highly significant (< .001). Our data suggest that the bone development of autistic boys should be monitored as part of routine care, especially if they are on casein-free diets.

Keywords  Autism – Autism spectrum disorder – Boys – Bone growth – Calcium intake – Dietary intake


This is a medical disclaimer: Please remember that this not meant as medical advice but as a desire to share information. Please always implement treatments under medical supervision. We are cannot be held liable for any of this information.


God bless


Miriam Jang MD



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